Fire crews are on the scene of a train derailment along the 7000 block of Grayson Road in Swatara Township. It happened just before noon.
Several rail cars are off the tracks, according to Dauphin County 911 dispatchers.
A Hazmat team is also on the scene.
No other details were immediately available.
Expect heavy traffic delays in the area and avoid Grayson Road if at all possible.